CD26: A prognostic marker of other systemic malignancies besides colo-rectal carcinomas

Role of MTHFR C677T polymorphism in systemic carcinogenesis, besides its role in the pathogenesis of colo-rectal carcinomas.

Skp2 and Its Emerging Role in the Pathogenesis of Systemic Malignancies Besides Breast Carcinomas

The recent article by Wang et al. (2012a) was highly interesting. Interestingly, recent data suggests that Skp2 expression may play a significant role in the etio-pathogenesis of a number of systemic malignancies besides breast carcinomas. For instance, the expression of Skp2 in prostate cancers is decreased by androgens and is mediated via pathways that are dependent on p107 as well as pathway...

[Prognostic factors in colo-rectal cancer].

● Background.—Under the auspices of the College of American Pathologists, the current state of knowledge regarding pathologic prognostic factors (factors linked to outcome) and predictive factors (factors predicting response to therapy) in colorectal carcinoma was evaluated. A multidisciplinary group of clinical (including the disciplines of medical oncology, surgical oncology, and radiation on...

sMICA and its emerging role as a prognostic and diagnostic indicator in systemic malignancies besides hepatocellular carcinoma

I read the recent article by Li . [1] with great interest. Intriguingly, emerging evidence suggests that soluble major histocompatibility complex class I­related chain A (sMICA) may be an important diagnostic and prognostic marker in a number of systemic malignancies besides hepatocellular carcinoma. For instance, higher sMICA levels are seen in oral squamous cell carcinomas of high TNM stages ...

Emerging Role of Geminin as a Prognostic Marker in Systemic Malignancies

I read with great interest the recent article by Bonito et al. [1] in a recent issue of your esteemed journal. The article is highly thought provoking. Geminin is rapidly emerging as a significant marker and prognostic indicator in a number of systemic malignancies besides breast malignancies. A worse clinical outcome and correspondingly a lower relapse-free survival rate are seen in salivary g...